Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-445-0
CAS number: 106-94-5
The genotoxic potential of n-propyl bromide was assessed by the Ames
test on five Salmonella typhimurium tester strains: TA1353,
TA1537, TA1538, TA98 and TA100, both in the absence and presence of
n-propyl bromide was dissolved and diluted in dimethyl sulfoxide and
tested at concentrations ranging from 100 to 10,000 µg/plate.
During the first genotoxicity study (HIS1005) performed at 100, 500,
1000, 5000 and 10,000 µg/plate, a slight toxic effect was observed
mainly at 10,000 µg/plate on the five tester strains with S9 mux and in
TA1535, TA 1538, TA98 and TA100 without S9 mix.
A second study (HIS1005A) performed at the same concentrations confirmed
In both studies, whether in the presence or in the absence of metabolic
activation, no increase was observed in the number of His+ revertant
colonies/plate at any of the concentrations tested, on the five tester
strains, with and without S9 mix.
In conclusion, n-propyl bromide was not genotoxic in the Ames test, with
or without metabolic activation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again