Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:
Migrated from Short description of key information:
A skin sensitization study according to the maximisation method of Magnusson and Kligman was performed on female Dunkin-Hartley guinea-pigs. The study was performed using the test substance 1-bromopropane and in accordance with OECD 406 and to GLP standard.
No cutaneous reactions possibly attributable to the sensitization potential of the test substance were observed and the material is therefore not classed as a sensitizer.

Justification for classification or non-classification

Based on the results of the skin sensitisation study, the test substance does not need to be classified for skin sensitisation according to Directive 67/548/EEC or Regulation (EC) No 1272/2008. No data are available for respiratory sensitisation.