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EC number: 202-767-9 | CAS number: 99-57-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
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- Additional toxicological data

Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05.02.2013 - 13.02.2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- Experimental test result performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- other: Gravimetric method
- Principles of method if other than guideline:
- Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
- GLP compliance:
- no
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 2-amino-4-nitrophenol
- Molecular Formula: C6H6N2O3
- Molecular Weight: 154.125 g/mol
- SMILES Notation: C1=CC(=C(C=C1[N+](=O)[O-])N)O
- InChI: 1S/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2
- Substance type: Organic
- Physical state: solid - Key result
- Medium:
- methanol
- Solubility:
- 3 900 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Soluble
- Conclusions:
- The experimental value of solubility of 2-amino-4-nitrophenol in methanol at 25 degC was determine to be 3900 mg/L indicating that this substance is soluble in methanol.
- Executive summary:
The experimental value of solubility of 2-amino-4-nitrophenol in methanol at 25 degC was determine to be 3900 mg/L indicating that this substance is soluble in methanol.
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05.02.2013 - 13.02.2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- Experimental test result performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- other: Gravimetric method
- Principles of method if other than guideline:
- Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
- GLP compliance:
- no
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 2-amino-4-nitrophenol
- Molecular Formula: C6H6N2O3
- Molecular Weight: 154.125 g/mol
- SMILES Notation: C1=CC(=C(C=C1[N+](=O)[O-])N)O
- InChI: 1S/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2
- Substance type: Organic
- Physical state: solid - Key result
- Medium:
- other: Petroleum ether
- Solubility:
- 110 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: moderately soluble
- Conclusions:
- The experimental value of solubility of 2-amino-4-nitrophenol in Petroleum ether at 25 degC was determine to be 110 mg/L indicating that this substance is moderately soluble in petroleum ether.
- Executive summary:
The experimental value of solubility of 2-amino-4-nitrophenol in Petroleum ether at 25 degC was determine to be 110 mg/L indicating that this substance is moderately soluble in petroleum ether.
Referenceopen allclose all
Description of key information
Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of 2-amino-4-nitrophenol in methanol at 25 degC was found to be 3900 mg/L indicating that the substance is soluble in methanol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 110 mg/L at 25 °C, indicating that the substance is moderately soluble in petroleum ether. The solubility value of 2-amino-4-nitrophenol in methanol at 20 degC is equivalent to a value of 3120 mg/L.
Key value for chemical safety assessment
- Solubility in organic solvents at 20°C:
- 3 120 mg/L
Additional information
Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of 2-amino-4-nitrophenol in methanol at 25 degC was found to be 3900 mg/L indicating that the substance is soluble in methanol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 110 mg/L at 25 °C, indicating that the substance is moderately soluble in petroleum ether. The solubility value of 2-amino-4-nitrophenol in methanol at 20 degC is equivalent to a value of 3120 mg/L.
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