Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

In the MITI list (1987), DPG (1,3 -diphenylguanidine) is described as a substance with at most a slight accumulation potential in biological material. The measured log Kow value comes to reinforce this assumption. Considering these results we can make the assumption that DPG is characterized by a low potential of adsorption. That is the reason why we propose to not perform a test. On the top of that, an oldest study already exists, nevertheless very little information are available on this data in order to challenge its validity. Effectively, a study on the bioaccumulation of DPG, following test regulations similar to OECD 305C (1981), exising Cyprinus carpio for 6 weeks in a flow through system (0.2 - 0.8 ml/min; 25 +/-2°C; O2 content: 6 -8 mg/l; solubilizer was not specified), permitted to estimate a BCF of <2 and <20 at exposure concentration of 0.1 and 0.01 mg/l respectively. The substance concentration in the test medium was analyzed twice a week (CITI, 1992). As a consequence, this study is used as a supporting data in order to confort the waiving proposal.

Based upon these results and on the log Kow value (=2.42), it can be assumed that DPG is characterised by a low potential of bioaccumulation in aquatic organisms.