Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
30 µg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
14 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
3 µg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
1.47 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
2.51 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.251 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.404 mg/kg soil dw
Assessment factor:
1 000

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

According to 67/548 EC and the results mentioned hereafter, 1,3-diphenylguanidine is classified as R51/53.

* Short term Toxicity to Fish:LC50-96h = 4.2 mg/l

Based on the results of this study, 1,3-diphenylguanidine would be classified as toxic to fish in accordance with the Directive 67/548/EC.

* Short term toxicity to aquatic invertebrates:EC50-48h = 17 mg/L .

Based on the results of this study, 1,3-diphenylguanidine is classified as toxic for aquatic invertebrates in accordance with the Directive 67/548/EC.

* Toxicity to aquatic algae:EC50-72h= 1.4 – 1.7 mg/L

According to EU regulation (Dir 67/548/EEC), in the tested conditions 1,3-diphenylguanidine is considered as toxic for algae based on growth rate.

* Toxicity to aquatic micro-organisms:EC50-3h=147 mg/L

Based on the results of this study, 1,3-diphenylguanidine shows low toxicity to activated sludge.

* 1 ,3-diphenylguanidine is not readily biodegradable

According to GHS-UN, these results are conclusive and so show that 1,3-diphenylguanidine is classified in the acute category II (Toxic to aquatic life) and chronic category II (Toxic to aquatic life with long lasting effects). According to CLP, 1,3 -diphenylguanidine is chronic II.