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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways


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Administrative data

Link to relevant study record(s)

Description of key information

1,3-diphenylguanidine is considered as hydrolytically stable. It should be noted that the newly discovered ready biodegradability of the substance could have allowed to waive the hydrolysis study.

Key value for chemical safety assessment

Additional information

Wohlfahrt, R. & Niebergall, H. (1984 and 1985) investigated the hydrolytic properties of DPG (0.3 g/l or 0.3 wt.% in water) in relation to the pH value at 80°C. In an acidic environment (pH 3.5) no recognizable hydrolysis of the original substance took place over a period of 500 hours. In the neutral range (pH 7) only 18.1% of DPG was hydrolyzed after 1000 hours. To investigate if DPG is hydrolysable, an OECD 111 study was conducted at pH 4 - 7 - 9. From the results, it can be concluded that the substance is stable in water at environmental pH.