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Environmental fate & pathways

Hydrolysis

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Description of key information

1,3-diphenylguanidine is considered as hydrolytically stable. It should be noted that the newly discovered ready biodegradability of the substance could have allowed to waive the hydrolysis study.

Key value for chemical safety assessment

Additional information

Wohlfahrt, R. & Niebergall, H. (1984 and 1985) investigated the hydrolytic properties of DPG (0.3 g/l or 0.3 wt.% in water) in relation to the pH value at 80°C. In an acidic environment (pH 3.5) no recognizable hydrolysis of the original substance took place over a period of 500 hours. In the neutral range (pH 7) only 18.1% of DPG was hydrolyzed after 1000 hours. To investigate if DPG is hydrolysable, an OECD 111 study was conducted at pH 4 - 7 - 9. From the results, it can be concluded that the substance is stable in water at environmental pH.