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Toxicological information

Carcinogenicity

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Description of key information

Key value for chemical safety assessment

Additional information

There is no evidence from the repeated dose studies that 1,3-diphenylguanidine is able to induce hyperplasia and/or pre-neoplastic lesions. In addition, the negative results from the series of in vivo genotoxicity tests do not suggest any cause for concern with respect to carcinogenicity

Justification for classification or non-classification

Mandatory classification :

- Regulation (EC) No 1272/2008 Annex VI Table 3.1

None

 

- Regulation (EC) No 1272/2008 Annex VI Table 3.2

None

 

Self-classification

- Regulation (EC) No 1272/2008

None

 

- Directive 67/548/EEC

None