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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment.

Data source

Reference
Reference Type:
publication
Title:
Contact dermatitis dur to spandex
Author:
Van Dijk E.
Year:
1968
Bibliographic source:
Acta Derm.Venereol. 48, 589-591.

Materials and methods

Study type:
clinical case study
Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Method

Type of population:
general
Subjects:
3 Women who have bra or brassiere with spandex.
Ethical approval:
confirmed, but no further information available
Route of exposure:
dermal
Reason of exposure:
unintentional, non-occupational
Details on exposure:
Exposure to spandex which contains DPG, e.g. brassiere, bra.
Examinations:
3 patients presented dermatitis.

Results and discussion

Clinical signs:
3 patients with contact dermatitis due to Spandex (a synthetic polyurethane elastomer) were tested; one patient showed a positive reaction to DPG (2 % in petrolatum) with erythema, edema, papules and vesicles.

Applicant's summary and conclusion

Conclusions:
3 patients with contact dermatitis due to Spandex (a synthetic polyurethane elastomer) were tested; one patient showed a positive reaction to DPG (2 % in petrolatum) with erythema, edema, papules and vesicles.