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EC number: 200-521-5
CAS number: 61-82-5
Long-term and short-term toxicity data are available for the three
trophic levels (fish, aquatic invertebrate and algae) in freshwater. Among
all data available, a toxic effect was observed for the aquatic
invertebrates. Daphnia magna is the most sensitive species with a
96h-LC50 value at 18 mg/L based
on nominal concentrations. A chronic study was performed on Daphnia
magna giving a 21-day NOEC (body length) of 0.32 mg/L and a 21-day
NOEC (reproduction) of 0.56 mg/L. For the algae, Pseudokirchneriella
subcapitata, the 72h-NOECr value based on growth rate is greater or
equal to 1.2 mg/L (the maximum concentration tested) based on measured
For fish, two acute studies were performed which resuilted in LC50s
(96h) greater than 1000 mg/L. While the long term (2 generation)
study in fish was not performed at a concentration high enough to be
able to define a genuine NOEC (maximum concentration test = 9 µg/L, well
below the NOEC for invertebrates and algae), the difference in
sensitivity of the fish and the invertebrates in the acute study is so
high that it is scientifically justifiable to consider the fish will not
be the most sensitive species and to use an assessment factor based on 3
long term studies.
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