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EC number: 200-521-5
CAS number: 61-82-5
The substance is very soluble, with pH dependency. The key value is
given for neutral (or basic) pH. In acidic medium (pH 4), saturation
could not be achieved.
An experimental study, conducted according to a recognized OECD/EC
method and under GLP, is available.
The substance being ionisable, determinations were conducted in buffers
at different pH, and not in pure water, which is a deviation to the
guideline. However, this providing additional information of scientific
interest, it was considered as acceptable. Results were >1384 g/L, 572,
264 and 261 g/L, respectively at pH 4.0, 4.8, 7.0 and 10.0. Considering
the substance is a primary amine, it exists mainly under its non-ionised
form -NH2, at pH at least 2 units above its pKa of ca 4.1. The trend
confirms that the higher solubility corresponds to the partially ionised
form in acidic medium. Results at pH 7.0 and 10.0 are identical; the
value as pH 7.0 is chosen as key data, as more environmentally relevant
than pH 10, and to be consistent with the definition of logKow presented
under IUCLID section 4.7.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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