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EC number: 235-252-2
CAS number: 12141-20-7
The potential toxicity of "LITHARGE lead oxide" was assessed in an acute
dermal irritation/corrosion test on three albino rabbits. In each
animal, 0.5 g of the solid test substance was applied on the right side
of the dorsal clipped region, the untreated left side served as control.
Exposure duration was 4 hours. Both sides were examined at 1, 24, 48,
and 72 hours after the end of exposure. The following results were
-No signs of erythema and oedema were observed
-No general toxic effects were seen
-The mean grades at 24, 48, and 72 hours after the end of exposure were
"0" in each animal.
The test article was classsified on the basis of the mean values of skin
reactions 24, 48 and 72 hours after the end of the 4-hour exposure
according to the EEC Directive 2001/59/EEC of 6 August 2001 and
Gefahrstoffverordnung (GefStoffV) of 15 November 1999 (BGB1. I, p.
2233). When applied to the skin, the test substance "LITHARGE lead
oxide" is classified as "non-irritant."
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