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EC number: 235-252-2
CAS number: 12141-20-7
A read-across approach was used from data for soluble Pb salts without
concern on the toxicity of the accompanying anion. All reliable toxicity
data selected for calculation of the PNEC were derived from soils spiked
with soluble lead salts (such as lead chloride, lead acetate and lead
nitrate). All results were based on elemental Pb concentrations,
allow-ing straight comparison of the results and read-across to other Pb
substances. Soil microbial process tests evaluate the native soil
microbial communities exposed to the substance. From the database of
lead toxicity to micro-organisms, there are 30 individual high quality
NOEC/EC10 values evaluating 5 functional parameters representing the
N-cycle (i.e. denitrification, N-mineralization and nitrification) and
the C-cycle (basal res-piration and substrate-induced respiration). The
selected NOEC and EC10 values on functional parameters vary from 97 (for
basal respiration) to 7880 mg Pb/kg dw (for potential nitrification
rate). Additionally, 23 NOEC or EC10 values are selected for 8 different
enzyme assays, ranging from 132 mg Pb/kg dw for dehydrogenase to ≥ 20720
mg Pb/kg dw for phosphatase. The ecological relevance of reduced
enzymatic activities is unclear and, therefore these data are not used
for PNEC calculation, but only presented as supporting evidence. The
results for the potential nitrification rate (PNR) are preferred above
data for the substrate induced nitrification (SIN). Theoretically, PNR
is a more sensitive endpoint compared to SIN because the sensitivity of
the latter can be ob-scured by substrate limitation.
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