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EC number: 220-688-8
CAS number: 2867-47-2
Measured concentration of MADAME during a 24 h exposure test condition:
Nominal conc. (mg/L)
Measured Conc. (mg/L)
Percent of nominal
Cummulative number of dead
Acute harmful for fish.
For the assessment of the acute toxicity to fish of the test substance
three studies are reported using three different fresh water species.
The results indicates that 2-dimethylaminoethyl methacrylate is acute
harmful to fish. For instance, in a GLP OECD guideline study with Oryzias
latipes as test organism a LC50 (96 h) of 19.1 mg/L was determined
using a semi-static test system. In contrast, no acute toxicity was
determined in a GLP DIN 38 412 L15 study with Leuciscus idus (LC50
(96 h) = 331 – 592 mg/L). Moreover, no acute toxicity was demonstrated
after 72 h of exposure to goldfish (LC50 = 139.5 mg/L).
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