Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

partition coefficient
Type of information:
Adequacy of study:
key study
Study period:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
QSAR based on two measured values (for Methyl lactate and 2-ethylhexyl lactate) and EPISuite generated values.
Partition coefficient type:
Key result
log Pow
Partition coefficient:
20 °C
Remarks on result:
other: QSAR-generated, based on measured values for ML and 2-EHL
The log Kow value for ethyl (S)-lactate is 0.31 at 20 °C.
Executive summary:

The EPI Suite-generated log Kow value for ethyl (S)-lactate is 0.31 at 20 °C.

Description of key information

The EPISuite-generated log Kow value for ethyl (S)-lactate is 0.31 at 20 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

The log Kow for methyl lactate (ML) and 2-ethylhexyl lactate (2-EHL) was measured using the OECD 117 HPLC method, yielding –0.2 for ML and 3.3 for 2-EHL. EPISuite-generated values for ML and 2-EHL are -0.67 and 2.69, respectively. Correlating EPISuite-generated values with experimental values yields the following property-property relationship: log Kow = 1.0417 × EPI-log-Kow + 0.4979 EPISuite generated log Kow value for ethyl (S)-lactate is –0.18. So the log Kow for ethyl (S)-lactate is 1.0417 × –0.18 + 0.4979 = 0.31