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EC number: 211-694-1
CAS number: 687-47-8
The decrease in breathing frequency together with the wet nares and
lachrymation are indicative of irritational properties of the test
Ethyl lactate was tested for its acute inhalation toxicity. Male and
female SPF-reared, Wistar derived rats were exposed to a concentration
of approximately 5.4 mg/L for 4 hours. A decreased breathing rate was
observed during exposure. Wet noses were seen after 30 minuter of
exposure and piloerection after 60 minutes. Half closed eyes and
lachrymation were all observed only at 15 minutes after the start of the
exposure. These signs had all disappeared the next day.All animals
appearde normal for the remainder of the 15 day observation period and
gained weight in a normal way. All animals survived till the end of the
study. Gross-examination at autopsy revealed pale lungs in one male and
three females. In three females the lungs showed a few petechiae. The
level of 5.4 mg/L was the maxiumum attainable concentration due to the
physical properties of the test material. Based on these results, the
LC50 of ethyl lactate is greater than 5.4 mg/L
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