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EC number: 203-678-8
CAS number: 109-53-5
IrritationContact period 5 minutes:Erythema: moderate to severe erythema at 24 and 48 hrs posttreatment developed into slight desquamation until day 8 inboth animals. Edema: well defined at 24 and 48 hrs post treatment, absenton day 8 post treatment in both animals.Contact period 2 hours:Erythema: moderate to severe erythema at 24 and 48 hrs posttreatment developed into superficial necrosis untilday 8 in both animals. Edema: well defined at 24 and 48 hrs post treatment, slightedema on day 8 post treatment in both animals.Systemic toxicityNo signs noted.
Two White Vienna rabbits receiced 0.5 mL undiluted test substance on the
shaved skin. The exposure duration was 2 h under occlusive conditions
(then washing off). The skin reactions were examined 24 & 48 h and 8
days post treatment. Score of erythema and edema were 2-3 in two
rabbits 24 and 48 h after application, the effects were not reversible;
superficial necroses developed within 8 days following application.
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