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EC number: 931-335-9
CAS number: 90622-74-5
For detailed results tables kindly refer to
the attached background materials section of the IUCLID.
A study was conducted to evaluate the skin
sensitisation potential of the test substance, C8-18 and C18-unsatd.
DEA, according to OECD Guideline 406 using guinea pig maximisation
assay. The procedure consisted of two parts: induction and challenge
exposures. For induction, three sets of intradermal injections were
given (0.1mL Freund's adjuvant; 0.1 mL of a 5% solution of test
substance in propylene glycol, and 0.1 mL of a 1:1 mix of Freund's
adjuvant and 5% test substance. One week after the injections, a 5% test
solution was placed on the skin over the injection sites via an
occlusive patch and left for 48 h. This was followed by a re-challenge:
14 days after the cutaneous exposure, 25% test substance in vaseline was
placed on the skin of the right flank (open application). Under the
study conditions, test substance did not produce any evidence of delayed
contact hypersensitivity and was therefore considered non-sensitising
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