Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 931-335-9
CAS number: 90622-74-5
study was conducted to determine the acute dermal toxicity of the test
substance, C8-18 and C18-unsatd. DEA, in male/female New Zealand White
rabbits. The procedure was the modification of the techniques described
in Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics,
compiled by the staff of the Division of Pharmacology, Food and Drug
Administration. A single dose of 2000 mg/kg bw of test substance was
applied to the abraded and intact skin of the test animals. The trunk of
each animal was then encased in a sleeve of plasticized material for a
24 h period. Animals were observed immediately after dosing, and at 1, 6
and 24 h post-dosing. Following the 24 h exposure period, animals were
observed for mortality, skin response and general behaviour for 14 d. No
mortality occurred. All animals appeared normal throughout the 24 h
exposure and 14 d post-exposure observation periods. Under the study
conditions, the dermal LD50 in rabbits was found to be > 2000 mg/kg bw
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again