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Sediment toxicity

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Description of key information

In accordance with column 2 of REACH Annex X, the long-term toxicity to sediment organisms study does not need to be conducted as the chemical safety assessment according to Annex I has not indicated a need to investigate further the effects of the substance and/or degradation products on sediment organisms.

Sediment effect values have been derived from a validated TLM-EqP modeling framework to provide additional data even though testing is not required. These data were considered reliable.

 The PNECs and hazard to sediment organisms was assessed by applying the equilibrium partitioning method (EqP) to the experimentally derived aquatic effect concentrations.

TLM QSAR modelling was used to estimate LL50 and NOELR values for L. variegatus. The calculated LL50 values were 22.498 - 75.783 mg/kg sediment dw and the NOELR values were 4.308 - 14.518 mg/kg sediment dw.

The lowest values were used for the chemical safety assessment.

Key value for chemical safety assessment

EC50 or LC50 for freshwater sediment:
22.489 mg/kg sediment dw
EC10, LC10 or NOEC for freshwater sediment:
4.308 mg/kg sediment dw

Additional information

A TLM-EqP modeling framework was used to support experimental values derived experimentally and are presented as supporting studies.

The estimated LL50 values from TLM QSAR were 22.489 - 75.783 mg/kg sediment dw and the NOELR values were 4.308 - 14.518 mg/kg sediment dw.