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EC number: 203-396-5
CAS number: 106-42-3
In accordance with column 2 of REACH Annex
X, the long-term toxicity to sediment organisms study does not need to
be conducted as the chemical safety assessment according to Annex I has
not indicated a need to investigate further the effects of the substance
and/or degradation products on sediment organisms.
Sediment effect values have been derived
from a validated TLM-EqP modeling framework to provide additional data
even though testing is not required. These data were considered
PNECs and hazard to sediment organisms was assessed by applying the
equilibrium partitioning method (EqP) to the experimentally derived
aquatic effect concentrations.
TLM QSAR modelling was used to estimate LL50
and NOELR values for L. variegatus. The calculated
LL50 values were 22.498 - 75.783 mg/kg sediment dw and the NOELR values
were 4.308 - 14.518 mg/kg sediment dw.
The lowest values were used for the chemical
A TLM-EqP modeling framework was used to
support experimental values derived experimentally and are presented as
The estimated LL50 values from TLM QSAR were
22.489 - 75.783 mg/kg sediment dw and the NOELR values were 4.308 -
14.518 mg/kg sediment dw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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