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EC number: -
CAS number: -
objective of this study was to determine the potential toxicity of
EXP0700332 when administered
by oral gavage to pregnant rats from implantation until the end of
gestation. Dosage levels of 0, 100, 300 and 1000 mg/kg/day were
administered to each animal once a day. The following parameters and end
points were evaluated in this study: clinical signs, body weights, food
consumption, gross necropsy findings, pregnancy performance and fetal
examinations. Administration of EXP0700332 at dose levels of up to 1000
mg/kg/day was not associated with any changes in clinical signs, body
weights, food consumption, necropsy findings, pregnancy performance or
fetal development. In conclusion, under the conditions of this study the
maternal and fetal no observed effect level (NOEL) was considered to be
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