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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 February 2009 - 03 July 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: OECD guidelines followed and statement of GLP
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Qualifier:
equivalent or similar to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
> 6.5
Temp.:
40 °C
pH:
6.9
Details on results:
See the attached Results.
Conclusions:
The partition coefficient has been determined to be >3.16 x 10 6 , log10 Pow >6.50 for the test material.
Executive summary:

The study was conducted in order to determine the general physico-chemical properties of the test material. The partition coefficient has been determined to be >3.16 x 106 , log10 Pow >6.50 for the test material.

Description of key information

A key GLP study, OECD 117, partition coefficient = >3.16 x 10 6 , log10 Pow >6.50.

Key value for chemical safety assessment

Log Kow (Log Pow):
6.5

Additional information

A key GLP compliant study conducted in accordance with the OECD 117 guideline, reported the partition coefficient to be Log Pow >6.50.