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Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 February 2009 - 03 July 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD guidelines followed and statement of GLP
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 0 g/L
- Temp.:
- 20 °C
- pH:
- 5.75
- Details on results:
- See table below.
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of the test material has been determined to be less than or equal to 0.0068 mg/l of solution at 20.0 ± 0.5°C. - Executive summary:
In this study the water solubility of the test substance was determined according to theprocedure outlined in the Organization for Economic Co-operation and Development (OECD) test guideline 105.
The water solubility of the test material has been determined to be less than or equal to 0.0068 mg/l of solution at 20.0 ± 0.5°C.
Reference
| Sample Number | Time Shaken at ~ 30ºC (hours) | Time Equilibrated at 20ºC (hours) | Concentration (g/l) | Solution pH |
| 1 | 24 | 24 | 4.11 x 10- 7 | 5.8 |
| 2 | 48 | 24 | 3.32 x 10 -6 | 5.8 |
| 3 | 72 | 24 | 6.80 x 10 -6 | 6.0 |
| 4 | 96 | 24 | 2.01 x 10 -4 | 5.6 |
| 5 | 120 | 24 | 6.73 x 10 -7 | 5.7 |
| 6 | 144 | 24 | 2.70 x 10 -6 | 5.6 |
Description of key information
A GLP study, OECD 105, water solubility = 0.0068 mg/l at 20.0 ± 0.5°C
Key value for chemical safety assessment
- Water solubility:
- 0.007 mg/L
- at the temperature of:
- 20 °C
Additional information
A GLP study conducted in accordance with the OECD 105 guideline, reported that the water solubility of the test material has been determined to be less that or equal to 6.80 x 1 0 -3 mg/l solution at 20.0 +/- 0.5°C.
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