Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: -
CAS number: -
Testing was not carried out according to Method C7 of Commission
Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD
Guidelines for Testing of Chemicals, 13 April 2004 for the following
1. The test material was determined, to have a very low water solubility
value of 0.0068 mg/l.
2. As the hydrolysis guidelines require an initial solution
concentration of less than half the water solubility, the test
concentration would need to be even lower than this. On top of that, the
guidelines also require the test material to be analytically measureable
at 10% of the initial test concentration, further increasing the
sensitivity that an analytical method would need to have. Test material
concentrations, even after being extracted to concentrate the samples,
would likely to be less than the limit of quantification.
3. At the low concentration that would be required for the hydrolysis
test, it would possibly be difficult to get near 100% recovery of test
material from the aqueous samples, as seen in the recoveries performed
for the water solubility. Loss of test material may be due to factors
like adsorption to glassware. If sample concentrations got even lower,
then recovery may reduce even further. The main functional groups in the
test material are imides and an amide. Neither of these functional
groups are normally susceptible to rapid hydrolysis under
environmentally relevant conditions, but both are known to hydrolyse
Biodegradation: in water screening test
Where no surfactant was present the test material attained 67%
degradation after 42 days (63 % degradation after 24 days). In the
presence of the surfactant, the test material attained 72% degradation
after 42 days. The OECD guideline criteria for classification of a
chemical as readily biodegradable are as follows: 1) percent
biodegradation must reach 60% within 28 days, and 2) the 60% degradation
must be attained within 10 days of exceeding 10% biodegradation.
Under the strict terms and conditions of OECD Guideline No 301B the test
material was considered to be rapidly biodegradable but it failed to
satisfy the 10-Day window validation criterion.
The BCF of a test substance in test fish were as follow: High
concentration level (0.2 mg/L) - A= BCFSS 56 (49-75*1), B= BCFSS < 87
(<60-87*2), C=BCFSS < 39 (<7-39*2) , D=BCFSS < 39 (3-39*2) and Low
concentration level (0.02 mg/L) - A=BCFSS < 90 (<59-90*2), B=BCF < 667
(<623-<667*3), C=BCFSS < 64 (<62-<64*2), D=BCFSS < 33 (<31-<33*2).
Transport and distribution: Absorption/desorption
During testing it was observed that these hydrocarbon structures did not
elute from a cyanopropyl solid phase HPLC column during the 45 minute
run time. The adsorption coefficient of duplicate determinations of
EXP0700332 test item was therefore determined to be as follows:
Log10 Koc of EXP0700332 >10.04 (retention time greater than 45 minutes
Koc of EXP0700332 > 1.10 x 10^10
Alternatively, the adsorption coefficient may be expressed as being
greater than that of 4,4’-DDT, the latest eluting reference standard
used. Since 4,4’-DDT has a theoretical adsorption coefficient of 5.63,
it may be stated that for EXP0700332:
Log10 Koc >5.63
Koc >4.27 x 105
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again