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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
The substance is a brown, viscous liquid.
Pour point: 200 ± 3 K
Boiling > 673 ± 0.5 K at 102.31 kPa
Density: 0.979 g/mL at 20.0 ± 0.5 °C
Particle size distribution (Granulometry): Not conducted as non-solid/granular form
Vapour pressure: 4.8 x 10-10Pa at 25 °C
Partition Coefficient > 6.5
Water solubility = 6.8 x 10-3mg/L solution at 20.0 ± 0.5 °C
Solubility in organic solvents: 1155 g/kg ± 34.5
Surface tension: not conducted as the water solubility was below 1 mg/L at 20 °C
Flash point: 211 ± 2 °C
Auto flammability: no auto-ignition temperature below 400 °C
Flammability: Waived based on chemical structure and flash point being more than 200 °C
Explosiveness: non explosive
Oxidising properties: obsolete
Dissociation constant: No observable dissociation
Additional information
JUSTIFICATION FOR USE OF READ-ACROSS DATA
There exists a previously notified ELINCS material with the name:
2,5-Pyrrolidinedione, 1, 1'-(iminodi-2,1-ethanediyl)bis[3-(octadecenyl)-. EC number 425-620-2
This material is considered to be a suitable analogue material for the Registration material by virtue of the similarity of chemistry and this is backed up by the similarity of physicochemical properties, and is further supported by similar toxicological and ecotoxicological data profiles. Both substances are alkenyl succinimide compounds, and the tested/Registration material differs from the analogue only by the alkylation of the secondary nitrogen.The difference between these two materials is that the tested material is alkylated with acetic anhydride, hence making the secondary amine less reactive. The alkyl chain length remains unchanged in comparison of these two materials. This ELINCS material has a complete EU base set for its previous registration and has been evaluated by the Competant Authority at that time and accepted. This registration material has been notified in Japan and is undergoing other global registration, and all of the information available supports the view that both of these materials have a very similar profile in properties. In addition to the almost complete structural similarities, similar physicochemical properties further support the justification for read across from this analogue to this Registration material e.g. similar physical states (brown, viscous liquids), similar density and having the same order of magnitude of partition coefficients. The chemistry is so similar that the reactivity and metabolism pathways are considered to be identical in biological systems, and so the toxicity profile is also very similar where testing information exist. Due to the alkylation, or capping, it is believed that the Registration substance will differ from the analogues material only in potentially demonstrating lower toxicity in comparison with the data for the surrogate/analogue substance. Therefore these data represent worst case hazard potential for the Registration material, and are considered to be an acceptable data set for the Registration material.
Read-across data are applied across many endpoints for this registration material as all the evidence supports the similarity of the profiles and thus it is considered that suitable data values can be predicted from the analogue material, saving animal testing and making maximum use of existing information.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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