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Environmental fate & pathways

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No experimental data on bioaccumulation are available for acetonitrile. Based onlow Kow values and high water solubility very low bioaccumulation potential is expected.

A bioconcentration factor for fish of 0.3 was calculated by Howard, 1993 using the log Pow= -0.34 value of Leo, 1971 and regression equations defined in Lyman et al (1982). This bioconcentration factor is in agreement with other calculated values which are in the range of 0.3-0.4 (EPA; 1991). An estimated BCF of 3 was calculated for acetonitrile by HSDB, 2009 using a log Kow of -0.34 (Hansch, 1995) and a regression-derived equation (Meylan, 1999). US EPA BCFWIN software (v2.17) generated an estimated BCF of 3.162 for acetonitrile based on the experimental log Kow of -0.34.

Regardless of the specific QSAR equation applied for these calculations the information consistently indicates a lack of bioaccumulation potential for acetonitrile in the environment.

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