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Environmental fate & pathways

Biodegradation in soil

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In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.  A half-life range for acetonitrile in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).   A waiver from further testing in soil is requested.

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Additional information

A half-life range for acetonitrile in soil of 168 -672 hours (1 -4 weeks) has been estimated from data on aqueous aerobic biodegradation (Howard et al. 1991).

Acetonitirile was used as the sole carbon and nitrogen source by Pseudomonas putida in soil and by Nocardia rhodochrus in barnyard soil (10 mg acetonitrile/ml); metabolites included ammonia, acetamide and acetic acid (Digeronimo and Antoine, 1976; Nawoz et al. 1989). In the study using Nocardia sp. 14% degradation occurred in 3 hours and 52% in 8 hours; the half-life was 7 hours.

The soil bacterium Aeromonas sp. BN 7013 and soil fungus Fusarium solani also grow using acetonitrile (Harper, 1977; Kuwahara et al. 1980).

A waiver from further testing in soil is requested on the basis that it is not scientifically justified because acetonitrile is readily biodegradable in reliable screening tests.