Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 695-022-6 | CAS number: 473278-76-1
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The endpoint “toxicity to terrestrial arthropods” is not a data requirement for the registered substance. However, for the sake of completeness this endpoint is covered by a short summary of the available data.
Two laboratory GLP studies are available in which the oral toxicity and contact toxicity of the test substance to honey bees (Apis mellifera L.) was investigated.
The first study investigated the oral toxicity of tefuryltrione to Apis mellifera, according to OECD 213 (1998). The substance was found to have a 72h LD50 of > 95.78 μg substance per bee.
In the second study the contact toxicity of tefuryltrione to Apis mellifera, was investigated according to OECD 214 (1998). The substance was found to have a 72 h contact LD50 of > 100 μg substance per bee.
In two more GLP studies the toxicity of the test substance on the parasitoid wasp Aphidius rhopalosiphi and the predatory mite Typhlodromus pyri was investigated.
In the first study, the effects of tefuryltrione on the survival of Aphidius rhopalosiphi were determined at a rate of 300 g a.i./ha, applied to barley seedlings (Hordeum vulgare). No mortality and no effect on reproductive success could be observed for the test item. Furthermore, compared to the control, no repellent effect was detected. The LR50 and the NOEC are at or above 300 g a.i./ha.
In the second study, the exposure of the predatory mite Typhlodromus pyri to tefuryltrione 19.0% w/w at a rate of 300 g a.i./ha resulted in no significant mortality or reduction of reproduction. The LR50 and the NOEC are at or above 300 g a.i./ha.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
