Registration Dossier
Registration Dossier
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EC number: 695-022-6 | CAS number: 473278-76-1
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The PBT Assessment is based on the criteria set out in the “Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment” (ECHA, 2017).
Persistence (P) Assessment
Tefuryltrione is not readily biodegradable according to OECD criteria (4% after 28 d, OECD 301F). The mineralisation rate, determined in a sediment simulation test, was 0.7 – 1% after 101 days based on the measured CO2 elevation). In the available studies on the aerobic transformation in soil the substance attained 11.5 to 63.2% degradation (elevation of 14CO2) after 120 days. The substance was not significantly degraded in soil under anaerobic conditions in the dark in the laboratory. The calculated half-lives under anaerobic conditions were > 1000 days.
Based on the available data, Tefuryltrione is assessed as persistent (P).
Bioaccumulation (B) assessment
Tefuryltrione has a low potential for bioaccumulation based on the log Kow and log D values < 3 (determined for pH 4 ,7 and 9).
Toxicity (T) assessment
Tefuryltrioneis is classified for specific target organ toxicity as STOT RE 1 (oral route) and STOT RE 2 (dermal route). The criteria for “T” based on mammalian effects are therefore met. Thus, the criteria set out in Annex XIII of Regulation (EC) No. 1907/2006 are met and the substance is considered to be T.
Summary and overall conclusions on PBT or vPvB properties
In conclusion, the substance is not PBT/vPvB
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