2-{2-chloro-4-mesyl-3-[(tetrahydrofuran-2-ylmethoxy)methyl]benzoyl}cyclohexane-1,3-dione

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be soluble in water to form a stable mixture

Reference 2

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Reference 3

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

26 Nov 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

GLP compliance:

yes (incl. QA statement)

Remarks:

Hess. Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

The test item, technical substance, is not a highly flammable solid in the sense of EU Method A.10.

The test item could not be ignited with a flame in the preliminary test. The test item melted.

Reference 4

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

17 Aug 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

GLP compliance:

yes (incl. QA statement)

Remarks:

Hess. Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

The test item, pure substance, is not a highly flammable solid in the sense of EU Method A.10.

The test item could not be ignited with a flame in the preliminary test.

Reference 5

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Version / remarks:

5th revised edition (2009)

GLP compliance:

yes (incl. QA statement)

Remarks:

Hess. Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz, Wiesbaden, Germany

Key result

Test procedure:

100 mm sample cube at 140°C

Max. temp. reached:

138

Induction time (h):

20

Result:

negative outcome (no effect observed)

Remarks on result:

other: At approx. 117 °C during the heat-up phase the test item melted and was flowed out of the basket.

The test item is not classified in Division 4.2 (self-heating substances) according to UN RTDG due to the fact that a negative result was obtained in the test using a 10 cm sample cube at 138 °C, according to the UN Test N.4.

Test in 10 cm sample cube at an oven temperature of 137 °C:

The oven temperature was adjusted to 140 °C. The temperature of the oven reached only 137 °and the test item temperature showed 138 °C. This could be explained to the different position of the two thermocouples. But these effects are not relevant for the result of the test. No exothermic effect has been observed at an oven temperature 137 °C for 20 h. At a temperature of approx. 117 °during the heat-up phase the test item melted and was flowed out of the basket. After approx. 21 hours the measurement was terminated, the mesh wire basket was empty.

The temperature of the test item did not exceed the oven temperature during the whole test.

Description of key information

Pure substance and technical substance: No ignition in the preliminary burning rate test (EU Method A.10).

Based on experience in handling and use and the chemical structure pyrophoricity and flammability on contact with water are not to be expected.

The Bowes-Cameron Cage Test showed a negative result (UN Test N.4), and therefore the substance does not need to be considered for classification as self-heating.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

The available data on flammability of the test substance do not meet the criteria for classification according to Regulation (EC) 1272/2008, and are therefore conclusive but not sufficient for classification:

No ignition in a test according EU Method A.10.

Based on chemical structure and experience in handling and use, pyrophoricity and flammability on contact with water are not expected.

The Bowes-Cameron Cage Test showed a negative result (UN Test N.4), therefore the substance does not need to be considered for classification as self-heating substance.