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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

On the basis of results obtained in the preliminary test, the definitive test was carried out at six concentrations of 4-chloro-α,α,α-trifluorotoluene (PCBTF) in a geometric series, namely 3.2, 10.1, 31.8, 100.8, 315.8 and 1000.4 mg/L.
The EC50 value with its 95% confidence limits and the NOEC after 3 hours of incubation, in terms of nominal test item concentrations, were as follows:
Time EC50 (mg/L) 95% LCL (mg/L) 95% UCL (mg/L) NOEC (mg/L)
3 hours 103.6 80.0 131.6 3.2

Key value for chemical safety assessment

EC50 for microorganisms:
103.6 mg/L
EC10 or NOEC for microorganisms:
0.32 mg/L

Additional information

The EC50 value and the NOEC for activated sludge microorganisms after 3 hours of incubation were 103.6 mg/L and 0.32 mg/L, based on nominal concentrations.