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EC number: 202-681-1 | CAS number: 98-56-6
The major route of exposure for workers is considered to be via inhalation. An inhalatory DNEL long term for systemic effects of 1.025 mg/m3 was calculated. Peak exposure via inhalation are possible, however no acute hazard was identified after inhalation of PCBTF, therefore no acute DNEL was calculated.
Dermal exposure is also possible, leading to systemic and local effects. A systemic long-term DNEL was calculated for workers based on oral-to-dermal extrapolation and resulted to be 0.4 mg/kg bw/day. The local acute DNEL was 17.6 µg/cm² based on skin sensitization, which was the most senstive endpoint. Dermal exposure of workers can be easily controlled by the use of appropriate PPEs.
The major route of exposure for the general population is considered to be via inhalation as PCBTF is persistent and volatile. An inhalatory DNEL long term for systemic effects of 0.255 mg/m3 was calculated. No peak exposure via inhalation is possible and no acute hazard was identified after inhalation of PCBTF, therefore no acute DNEL was calculated.
A systemic long-term DNEL was calculated for the dermal exposure based on oral-to-dermal extrapolation and resulted to be 0.2 mg/kg bw/day. The local acute DNEL for dermal exposure was 8.8 µg/cm² based on skin sensitization, which was the most senstive endpoint. The systemic long term oral DNEL was calculated to be 0.2 m/kg bw/d. However neither dermal nor oral exposure for the general population are expected.
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