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Physical & Chemical properties

Dissociation constant

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Endpoint:
dissociation constant
Type of information:
not specified
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No test substance information, no guideline, secondary literature, but reference database.
Guideline:
other: no data
GLP compliance:
not specified
Dissociating properties:
yes
Remarks on result:
other: Acid-base constant: pKa = 10.1
Endpoint:
dissociation constant
Type of information:
not specified
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary sources
Guideline:
other: no data
GLP compliance:
not specified
Dissociating properties:
yes
Remarks on result:
other: Acid-base constant: 10.05 - 10.27

Description of key information

pKa values range from 10.05 to 10.27

Key value for chemical safety assessment

Additional information

Two pKa values are reported in literature; since these values are in a narrow range, they have been used in a weight of evidence approach.