Registration Dossier

Administrative data

Endpoint:
other distribution data
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Only the removal of the substance from water is measured, no indication of possible metabolisation/degradation impact is provided. Single bacteria is used, therefore the result can not be extrapolated to the distribution in the environment.

Data source

Reference
Reference Type:
publication
Title:
BIOACCUMULATION OF P-METHOXYPHENOL AND 4-ISOPROPYLPHENOL ON ACINETOBACTER CALCOACETICUS ANITRATUS
Author:
Zaim KK
Year:
1991
Bibliographic source:
Doga - Tr. J. of Engineering and Environmental Sciences. 15 (1991), 39-53

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The bioaccumulation of the test substance by sub-surface bacterial biomass was performed by single-solute bioaccumulation isotherm in static
bottle test procedure.
The bioaccumulation was determined by the ratio between the concentration in the filtrate at each sampling time and the initial concentration of the test substance.
GLP compliance:
not specified
Type of study:
other: bioaccumulation by sub-surface bacterial biomass
Media:
other: water - bacterial biomass

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Identity: p-Methoxyphenol (no other information available).

Results and discussion

Any other information on results incl. tables

Bioaccumulation on 1000 mg/L biomass at high concentration:
- stationary mode (185.44 µg/L): from 0 to 15% of removal of the initial concentration
- low nutrient mode (101.57 mg/L): maximum of removal of 48% of the inital concentration at 10h, 

followed by a desorption

Bioaccumulation on 1000 mg/L biomass at low concentration:
- stationary mode (50.31 µg/L): maximum of 10% of removal of the initial concentration
- low nutrient mode (52.97 mg/L): maximum of 15% of removal of the inital concentration

Bioaccumulation on 500 mg/L biomass at high concentration:
- stationary mode (186.07 µg/L): maximum of 38% of removal of the initial  concentration
- low nutrient mode (249.99 mg/L): maximum of removal of 10% of the inital concentration.

Bioaccumulation on 500 mg/L biomass at low concentration:
- stationary mode (61.42 µg/L): maximum of 35% of removal of the initial concentration
- low nutrient mode (59.98 mg/L): maximum of 10% of removal of the inital concentration

Bioaccumulation on 300 mg/L biomass at high concentration:
- stationary mode (184.93 µg/L): maximum of 45 % of removal of the initial concentration
- low nutrient mode (222.26 mg/L): maximum of removal of 10% of the inital concentration.

Bioaccumulation on 300 mg/L biomass at low concentration:
- stationary mode (95.42 µg/L): maximum of 15% of removal of the initial concentration
- low nutrient mode (121.23 mg/L): maximum of 5% of removal of the inital concentration.

Applicant's summary and conclusion