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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Adequacy of study:
disregarded due to major methodological deficiencies

Data source

Reference
Reference Type:
publication
Title:
An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke.
Author:
Curvall M., Enzell C.R. and Pettersson B.
Year:
1984
Bibliographic source:
Journal Cell Biology and Toxicology, Vol. 1, p.173-193.

Materials and methods

Type of study / information:
Type: other: cytotoxicity: evaluation of the short-term tests for predicting the cytotoxicity

Test material

Constituent 1
Chemical structure
Reference substance name:
Mequinol
EC Number:
205-769-8
EC Name:
Mequinol
Cas Number:
150-76-5
Molecular formula:
C7H8O2
IUPAC Name:
4-methoxyphenol
Details on test material:
The origin of p-methoxyphenol was not reported.

Results and discussion

Any other information on results incl. tables

Based on its toxicity in all four systems (A(cg)=9, A(om)=1, A(ca)=0 and  A(md)=0) 
p-methoxyphenol showed a low mean activity, A(t) = 2.5.

Applicant's summary and conclusion