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No data are available. As the substance is a water soluble salt of phosphate, effects can be read-across from the cation, which is likely to have the more important effects.Inbiological systems, phosphate is an abundant in cells and body fluids.In ecological terms, because of its important role in biological systems, phosphate is a highly sought-after resource. Thus, read-across from component CAS Reg.-No. 108-78-1, melamine, is justified.

Three experimental determinations of the bioconcentration factor BCF in 3 species of fish were reported (2 times Lech 1984; Nite 2010). The BCF was <1 in each case, except for the Nite study with the lower concentration of 0.2 ppm in water, where the BCF was 3.8.

An older and less reliable estimation (ECETOC 1983) of the BCF, based on the water solubility of melamine, yielded BCF = 15.

Altogether it is unlikely that melamine could bioaccumulate to a relevant degree.