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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The toxicity of melamine to algae, as measured by growth inhibition, is low.

Key value for chemical safety assessment

EC50 for freshwater algae:
325 mg/L
EC10 or NOEC for freshwater algae:
98 mg/L

Additional information

As the substance is a salt of phosphate, effects can be read-across from the cation, which is likely to have the more important effects. Inbiological systems, phosphate is an abundant in cells and body fluids. In ecological terms, because of its important role in biological systems, phosphate is a highly sought-after resource. Thus, read-across from component CAS Reg.-No. 108-78-1, melamine, is justified. All effect values are minimum values as the molar ratio anion:cation equals 1.74.

The results are summarized in the table below. The studies revealed EC50 values of 325 and 940 mg/L, respecitively. The NOEC values were determined to be 98 and 320 mg/L. The compound is not expected to have significant effect on aquatic algae and cyanobacteria.

 Study  Species  Effect  Remarks
Drozdowski 1988

Pseudokirchneriella subcapitata

 EC50 = 325 mg/L /  NOEC = 98 mg/L

 conducted with CAS 37640 -57 -6

Oldersma 1982

 Scenedesmus panonicus

 EC50 = 940 mg/L / NOEC = 320 mg/L

 conducted with CAS 37640 -57 -6