Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The substance is acutely not harmful to freshwater invertebrates.

Key value for chemical safety assessment

Additional information

As the substance is a salt of phosphate, effects can be read-across from the cation, which is likely to have the more important effects. Inbiological systems, phosphate is an abundant in cells and body fluids. In ecological terms, because of its important role in biological systems, phosphate is a highly sought-after resource. Thus, read-across from component CAS Reg.-No. 108-78-1, melamine, is justified. All effect values are minimum values as the molar ratio anion:cation equals 1.74.

The results of the studies are summarized in the table below. Both mortality as regulatorily relevant values as well as mobility/behavior as additional endpoints were assessed. Effects on mortality revealed LC50 values > 1000 mg/L. However, slight effects on mobility/behavior could be detected at lower concentrations. Here, the EC50 values were at 200 mg/L and < 180 mg/L, respecitively. The substance is acutely not harmful to aquatic invertebrates.

 Study  Species  Effect  Remarks
Frazier 1988

 Daphnia magna

 LC50 > 1000 mg/L (mortality) /  EC50 = 200 mg/L (mobility/behavior)

 conducted with CAS 37640 -57 -6

Adema 1978

 Daphnia magna

 LC50 > 2000 mg/L (mortality) / EC50 < 180 mg/L (mobility/behavior)

 conducted with CAS 37640 -57 -6