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Description of key information

Melamine is a stable molecule that is hydrolyzed only by mineral acid or inorganic alkali. Hydrolysis proceeds stepwise, with loss of one, two, or all three amino groups, i.e. producing ammeline, ammelide and cyanuric acid. The product spectrum varies with temperature, pH, and concentration; the end product is cyanuric acid [108-80-5]. 
The rate constants at 100 °C are: k(s-1) = 3.80 x 10exp-5 [OH-] respectively k(s-1) = 1.25 x 10exp-4[H +].

Key value for chemical safety assessment

Additional information

A weight of evidence approach from the consistent statements in the 2 handbooks (Gmelin 1971 and Ullmann 2006) is applied.