Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Warbrick et al. (2001) reported the outcome of a local lymph node assay. 1,1 -dichloroethene failed to induce an increase of the stimulation index above 3 at all tested concentrations . A stimulation index for 1,1 -dichloroethene of 0.91 was observed at the highest tested concentration of 50 %.

Therefore, according to this study, 1,1-dichloroethene is not a dermal sensitizer.


Migrated from Short description of key information:
1,1-dichloroethene, up to 50 % in acetone/olive oil, failed to induce an increase of the stimulation index in the Local Lymph Node Assay.

Respiratory sensitisation

Endpoint conclusion
Additional information:

No information is available about respiratory sensitisation.


Migrated from Short description of key information:
No information is available about respiratory sensitisation.

Justification for classification or non-classification

Based on the negative results of a local lymph node assay, classification of 1,1 -dichloroethene as a sensitizer is not considered necessary.