Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: acceptable well-documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982
Report date:
1982

Materials and methods

Endpoint addressed:
skin irritation / corrosion
Principles of method if other than guideline:
other: Repeated Insult Patch Test modified Shelanski (4 x 4 Method)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(morpholinothio)benzothiazole
EC Number:
203-052-4
EC Name:
2-(morpholinothio)benzothiazole
Cas Number:
102-77-2
Molecular formula:
C11H12N2OS2
IUPAC Name:
2-(morpholin-4-ylsulfanyl)-1,3-benzothiazole
Details on test material:
N-oxydiethylene-benzothiazole sulphenamide, brown granules

Results and discussion

Results:
Irritation:
The test material elicited irritation in 31/49 individuals.

Applicant's summary and conclusion