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EC number: 203-052-4
CAS number: 102-77-2
In up-to-date assessment, latest and more reliable data are found and
hence used for the estimation of PNEC values. This also led to the
change in classification from R51/53 to R50/53.
In Directive 67/548/EEC and the regulation (EC) No 1272/2008,
2-(morpholin-4-ylsulfanyl) -1,3-benzothiazole has been legally
classified as "Toxic to aquatic organisms, may cause long-term adverse
effects in the aquatic environment" with the phrase of R 51/53 in Annex
I and aquatic chronic 2 (H411), respectively. According to the
up-to-date information listed below, a stricter self-classification has
been proposed in this dossier as “Very toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment" with the
phrase of R 50/53 and aquatic acute 1 (H400) and aquatic chronic 1
- The most sensitive acute toxicity is to fish (Oncorhynchus mykiss): 96
hour-LC50 of 0.31 mg/L (Monsanto, 1981a).
- The most sensitive chronic toxicity of MBT (read-across of one main
degradation product) was determined in a long-term study with fish
(rainbow trout): NOEC (89d) of 0.041 mg/L (CMA, 1989).
- Measured log Pow of 3.4 (Currenta, 2010c), which is higher than 3.
- MBS is not readily biodegradable (Bayer AG, 1988a).
With the data listed above, MBS should be classified as aquatic acute 1
(H400) and aquatic chronic 1 (410) according to GHS (Regulation EC
1272/2008) and as R50/53 according the Directive 67/548/EEC. The
appropriate multiplying factors for acute and chronic toxicity are both
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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