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EC number: 201-645-2
CAS number: 85-98-3
test substance, Centralit, was tested for the assessment of eye
irritation/corrosion effects using albino rabbit (New Zealand Albino
test was performed according to the Method B.5 Acute Toxicity: Eye
Irritation/Corrosion. Council Regulation (EC) No.440/2008, published in
O.J. L 142, 2008.
test was performed initially using one animal. Because a corrosive or
severe irritating effects were not observed in initial test, the
response was confirmed using two additional animals.
following changes were observed on eye at 1 hour after application:
conjunctivae – diffuse, crimson colour, individual vessels not easily
discernible in all rabbits and some swelling above normal in one rabbit
(No. 16). At 24, 48 and 72 hours after application no irritating effects
of eye was observed in all animals.
clinical signs of systemic intoxication were detected.
of results after single application demonstrated that the test
substance, Centralit, is not irritating for eye of rabbit.
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