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EC number: 201-645-2
CAS number: 85-98-3
No experimental data are available
on the bioconcentration of Ethyl centralite by aquatic organisms.
The literature data are available
(supporting information). These data are based on the calculated values
of log Kow.
(Q)SAR model EPI Suite for
predicting fish BCF was used. The experimental value of log Kow (log Kow
= 3.98) is used for (Q)SAR. The calculated BCF value is 196.3 L/kg.
The experimental value of log Kow
(3.98) is higher than 3 which is the threshold value for the data
waiving according to Annex IX of REACH Regulation.
The experimental value log Kow is
smaller than 4.5 which is the threshold value for PBT/vPvB assessment
according to Annex XIII of REACH Regulation (Screening information as
listed in Section 3.1 of Annex XIII to the REACH Regulation). The
calculated BCF value is 196.3 L/kg. This value is smaller than 2000 (PBT
and vPvB criteria according to Section 1 of Annex XIII to the REACH
Regulation), resp. this value is notclosed
to the threshold values of either 2000 for 'B' or 5000 for 'vB'.
Based on above mentioned information
the conclusion is the substance does not fulfil the B/vB criteria.
In addition, the performing of
Bioaccumulation in fish: aqueous or dietary bioaccumulation fish test
(OECD TG 305) involves animal testing.
Therefore the study is
scientifically not necessary.
BCF = 196.3 L/kg was chosen as key value for CSA. This value is based on
experimental value log Kow = 3.98
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