Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-506-8
CAS number: 4390-04-9
No additional data
data is being read across from the source study that tested Paraffin
(petroleum), normal, C5-C20 based on analogue read across.
was tested for acute oral toxicity in Sprague-Dawley rats in a limit
The test substance, a liquid, was administered as supplied. Animals were
fasted overnight prior to treatment. The assay was conducted on a group
of 10 rats (5 males, 5 females) with a dose of 5000 mg/kg b.w.
administered by gavage (via a syringe) in a single oral dose.
for mortality, clinical signs and body weight gain were performed during
the 14-day observation period. All surviving animals were necropsied at
the end of the observation period.
No deaths occurred during the study. Body weight gain was not affected
by treatment. A/G staining was noted in all animals within the 6-hour
observation period. In-life observations also included alopecia and
unkempt coat. At necropsy, macroscopic examination of main organs showed
lung discoloration in seven animals.
As the acute oral LD50 was found to be greater than 5000 mg/kg b.w.
under the conditions of the test, MRD-83-207 is not classified according
to the criteria of Annex VI to Directive 67/548/EEC and CLP Regulation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again