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EC number: 224-506-8
CAS number: 4390-04-9
In instances where stable aerosol formation
is expected, a value of 10 mg/m3 will be used as an
operational control limit for inhalation exposure.
studies of the substances to be registered or similar materials used for
read-across purposes have been conducted to assess the hazard
properties. Data from acute toxicity studies (oral, dermal, inhalation
routes) as well as available longer term repeat dose toxicity (oral and
inhalation routes) studies demonstrate the lack of adverse effects
subsequent to exposure to these substances tested to maximally
attainable vapor concentrations, limit doses, or to other limits imposed
by safety considerations. As no effects were demonstrated, the data are
not appropriate for DNEL derivation. As these hydrocarbon solvents are
demonstrably not hazardous for effects which are quantifiable, human
health exposure assessments have not been conducted.
to comply with standard information requirements, OECD Guideline 90-day
sub-chronic (OECD 408), OECD Guideline 414 (Rat and Rabbit)
developmental toxicity, and OECD Guideline 443 extended one-generation
reproductive toxicity tests are proposed. Should adverse
treatment-related effects be observed in any of the above studies (once
completed), this section will be amended accordingly with derivation of
appropriate DNELs for Workers and General Population.
Aspiration is a potential hazard, but a DNEL
calculation is not appropriate for an aspiration hazard.
Workers are expected to have infrequent and
Consumers in the general population are
expected to have infrequent and short-term exposures.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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