Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 275-702-5
CAS number: 71617-10-2
Under the experimental conditions described in the report, the mean
score for erythema and oedema in the 4 rabbits used were as follow:
The primary skin irritant effect of Neo Heliopan E1000 was
investigated according to the method recommended in the current OECD
guideline no. 404, "Acute Dermal Irritation/ Corrosion", 1992, and in
the current EC guideline B.4 "Acute toxicity (skin irritation)", dated
29.12.1992. The study was extended to investigate 5 different
concentrations of the test article and a vehicle control on each animal.
Four albinos rabbits were exposed to different concentrations of
the test article at 6 skin sites on the back. After 4 h of exposure, the
test article was removed and the skin was examined 1, 24, 48, and 72 h
after termination of exposure.
Slight skin erythma was observed at 1 to 48 h after termination of
exposure of the neat test article. Apart from that, no abnormalities
Accordingly, isopentyl p-methoxycinnamate was rated
as being not irritating to the skin of rabbits.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again