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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010-04-21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 1
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
no
Type of method:
method to determine freezing temperature
Test material information:
Composition 1
Melting / freezing pt.:
3.5 °C
Atm. press.:
ca. 100.9 kPa
Decomposition:
no
Sublimation:
no
Conclusions:
The melting / freezing point of Isopentyl p-methoxycinnamate was 3.5 °C at 100.9 kPa.
Executive summary:

The melting point of the test substance determined in accordance with EU A1 was 3.5°C at mospheric pressure (100.9 kPa).

Description of key information

The melting / freezing point of Isopentyl p-methoxycinnamate was  3.5 °C at 100.9 kPa.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
3.5 °C

Additional information

The melting / freezing point of the test substance was determined according to EU method A1. Using this method the melting point of the test substance was determined to be 3.5 °C at atmospheric pressure.

Result of the screening test:

The sample stored at 4°C remained unfrozen after 24 h of storage, while the two samples stored at -20°C and -80°C were found to be frozen.

Results of the accurate test:

"Test 1 initial":

The temperature was slowly lowered to -9.5°C over a period of approximately 40 min and the temperature of the test substance was measured every 30 s from 3.5°C onwards, at which point the sample was very viscous but not solid and further temperature change was not observed. 

"Test 1 repeat":

The temperature profile was the same as for "Test 1 initial" but was run over a longer period of approximately 60 min. When the temperature had reached -9.5°C, a seed crystal from an aliquot of sample frozen at -80°C was added to the test solution. The test solution immediately solidified, the temperature immediately dropped to -10.5°C and then rose over a period of 2 min to a steady state temperature of 3.5°C for approximately 5 min before the temperature decreased again. The test solution remained solidified during the increase in temperature from -10°C to 3.5°C. 

"Test 2":

This test was performed like "Test 1 repeat" but with the temperature of the test substance being measured every 30 s from 3°C onwards. The temperature slowly lowered to -9.5°C over a period of approximately 77 min. Once the temperature had reached -9.5°C, a seed crystal from an aliquot of sample frozen at -80°C was added to the test sample. The test solution immediately solidified and the temperature immediately dropped to -10.5°C and then rose over a period of 3 min to a steady state temperature of 3.5°C for approximately 7 min before the temperature decreased again. The test solution remained solidified during the increase in temperature from -10°C to 3.5°C.

 

From the results of the 3 experiments it was concluded that the melting / freezing point of test substance is 3.5°C.

This value corresponds to the average of the first 5 consecutive readings, during which the temperature of the solidified test solution remained constant within ±0.5°C.