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EC number: 275-702-5
CAS number: 71617-10-2
Group I conjunctivae
Group II conjunctivae
Group III conjunctivae
The eye irritation potential of 2-ethylhexyl 4-methoxycinnamate, a close
structural analogue of isopentyl p-methoxycinnamate, was evalauted in a
Draize test in albino rabbits.
was injected into the left eye of 3 albino rabbits without rinsing, the
left eye of another 3 albino rabbits were rinsed after 2 and 4 seconds,
resp. Cornea, iris, and conjunctivae were examined. A slight irritation
of the conjunctivae was observed during the few hours after application
. This irritation is manifested by the presence of some more capillaries
injected into the eye treated than on the eye not treated. No effect,
however small, could be detected 24 h after application of the test
In view of the close chemical relationship between isopentyl
p-methoxycinnamate and Neo Heliopan AV, the negative findings obtained
provide further evidence for the non-eye-irritancy of isopentyl
p-methoxycinnamate in rabbits.
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