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EC number: 451-160-7
CAS number: 17913-76-7
All animals survived the 2000 mg/kg oral dose.
Bodyweight changes were normal.
Instances of dyspnea, anogenital area wet, chromorhinorrhea and
localized alopecia were noted during the observation period.
Necropsy results were normal.
The oral LD50 value of 2,4,7,9-tetramethyldecane-4,7-diol in rats is greater than 2000 mg/kg body weight.Three healthy male and three healthy female Wistar albino rats were dosed orally with 2,4,7,9-tetramethyldecane-4,7-diol at 2000 mg/kg. The rats were observed 1, 2, 3, and 4 hours post-dose and once daily for 14 days for mortality, toxicity and pharmacological effects. Body weights were recorded immediately pretest, weekly, at death and at termination in the survivors. All animals were examined for gross pathology. The test article was assigned to be a toxic class based on the mortality response noted.All animals survived the 2000 mg/kg oral dose.Body weight changes were normal.Instances of dyspnea, anogenital area wet, red nasal discharge, and localized alopecia were noted during the observation period.Necropsy results were normal.
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