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EC number: 206-354-4
CAS number: 330-54-1
All available experimental data on skin and eye irritation indicate Diuron is not irritant or corrosive.
was tested for its skin irritation potential according to OECD Guideline
404 (Sharp, 1997). The shaved skin of three male New Zealand rabbits was
exposed to unchanged test material (0.5 g) for 4 hours under
semi-occlusive conditions. No signs of erythema or oedema were observed
at any of the time points in any of the rabbits. Diuron was therefore
considered as not irritating to rabbit skin.
was examined for its eye irritation potential in a study performed
according to OECD Guideline 405 (Sharp, 1997). 0.1g
undiluted test substance was instilled to the right eye of 3 rabbits
(New Zealand White). The substance did not cause any effects with
regards to corneal opacity or iris lesions. Only very slight
conjunctival redness and oedema were observed but these effects were
fully reversible within 72 hours.
available data on irritation is conclusive but not sufficient for
classification according to directives DSD
(67/548/EEC) or CLP (1272/2008/EC).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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